Advanced nanoplatform for modulated macrophage phenotype and enhanced gene delivery against bacterial infection

This project focuses on designing functional nanomaterials to regulate macrophage polarization and improve gene delivery efficiency for antibacterial applications. By leveraging nanotechnology and immunoengineering, we aim to enhance the immune response against bacterial infections through targeted mRNA delivery and macrophage phenotype modulation. The project integrates materials chemistry, biotechnology, and drug delivery strategies to develop innovative therapeutic solutions.

The program will leverage multidisciplinary research expertise and advanced facilities at UQ in materials science and bioengineering. I will be mainly based at the Australian Institute for Bioengineering and Nanotechnology (AIBN) at UQ, where the student will be mentored by Dr. Yue Wang and Prof Chengzhong Yu,  experts in material synthesis for biomedical applications. AIBN is a world-leading institute with state-of-the-art facilities including material synthesis, characterisation and animal facilities, which will be used in this program. Collaboration with Prof Matt Sweet from the Institute for Molecular Bioscience, UQ, a leading expert in immunology and molecular biology, will provide valuable guidance and technical support for macrophage study.

This project is supported by the Research project scholarship.

Learn more about the Research project scholarship.

Your application will be assessed on a competitive basis.

We take into account your:

• previous academic record
• publication record
• honours and awards
• employment history

A working knowledge of nanotechnology, biotechnology, materials engineering, and immunology would be of benefit to someone working on this project.

You will demonstrate academic achievement in the field/s of biomaterials, MRNA delivery platform and the potential for scholastic success.

A background or knowledge of biotechnology, nanomedicine or other interdisciplinary research fields is highly desirable.

Before you apply

Before submitting an application you should:

1. check your eligibility for a Doctor of Philosophy (PhD)
2. prepare your documentation
3. contact Dr Yue Wang ([email protected]) to discuss your interest and suitability
4. submit your application by 1 May, 2025 1 May, 2025.

When you apply

You apply for this scholarship when you submit an application for your program. You don’t need to submit a separate scholarship application.

In your application ensure that under the ‘Scholarships and collaborative study’ section you select:

• ‘My higher degree is not collaborative’
• ‘I am applying for, or have been awarded a scholarship or sponsorship'
• ‘Other’, then ‘Research Project Scholarship’ and in the ‘Name of scholarship’ field enter NANOPLATFORM-WANG.

Apply now